72 studies on Semax curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
Independent certificate-of-analysis evidence from third-party labs — the data behind the studies. Updated as new COAs are verified. Read the full grey-market analysis →
| Manufacturer | Batches | Avg purity | |
|---|---|---|---|
| Allen Biotechnology Co Abc | 7 | 99.83% | View COA → |
| Modern Research LLC | 5 | 99.75% | View COA → |
| PGB | 5 | 99.49% | View COA → |
| Qingdao Sigma Chemical | 4 | 99.74% | View COA → |
| Homopeptide | 4 | 99.37% | View COA → |
| EZP | 3 | 99.65% | View COA → |
| Eternal Peptides | 3 | 99.52% | View COA → |
| MKM Peptides | 3 | 99.47% | View COA → |
Recent certificates: #14820 (99.015%) · #14577 (99.154%) · #13239 (98.091%) · #12961 (99.58%) · #12209 (99.497%) · #14162 (99.019%)
Manufacturers with published third-party certificates of analysis for Semax. Open a vendor to see every batch we've verified.
This research represents a substantial advancement in the field of formal software verification, particularly for the widely used C language. The ability to formally verify software components with greater precision a…
This study provides strong preclinical evidence for Semax's potential as a therapeutic agent for stress-induced anxiety and depression. Given that Semax is a well-studied peptide already used clinically in some countr…
These findings strongly suggest that Mexidol and Semax, particularly in combination, could be highly effective neuroprotective and cognitive-enhancing agents for conditions involving hypoxic brain injury. Their abilit…
This pilot study provides compelling evidence that Semax and PGP possess significant neuroprotective and regenerative properties in the context of experimental ischemia. The ability to improve cell morphology and stim…
This research provides compelling evidence that simple proline-containing peptides can offer significant protection against stress-induced hypercoagulation, a critical factor in cardiovascular disease. The activation …
This research highlights a potentially significant role for semax as a novel therapeutic agent in managing and preventing stress-induced hypercoagulation. Given that chronic physiological and psychological stress are …
These findings are crucial as they suggest that Semax's nootropic and analgesic effects involve distinct mechanisms and potentially different brain regions. Understanding these route-dependent differences allows for o…
This research is significant because enhanced proteolytic stability is a critical factor for improving the pharmacokinetic profile and therapeutic efficacy of peptide-based drugs like Semax. By identifying specific N-…
These findings highlight the significant neuroprotective potential of Semax and its fragment PGP by enhancing the brain's natural repair mechanisms following ischemic injury. By upregulating critical neurotrophins and…
This study provides compelling evidence that Semax can effectively reverse long-lasting behavioral and cognitive deficits induced by early life stress in rats. This highlights Semax's potential as a therapeutic agent …
This research provides compelling evidence that Semax and Pro-Gly-Pro could be promising therapeutic agents for ischemic stroke by beneficially modulating the VEGF system. Their ability to normalize detrimental gene e…
This research highlights that Semax shows promise as a therapeutic agent for addressing behavioral and developmental deficits induced by early life stress, such as maternal deprivation. The ability of Semax to normali…
This research provides compelling evidence that nootropic drugs can effectively improve cognitive and emotional behaviors, particularly in individuals (or in this case, mouse strains) predisposed to higher anxiety and…
This research highlights potential therapeutic strategies for mitigating the devastating effects of focal brain ischemia, particularly in critical areas like the prefrontal cortex, which is vital for executive functio…
This research underscores Semax's significant potential as an antistress agent, specifically in protecting vital immune organs like the spleen from stress-induced damage. Its ability to reduce macrophage proliferation…
This review underscores the significant therapeutic potential of peptide bioregulators for age-related neurological conditions and cognitive decline. By consolidating evidence on both complex and short peptides, it pr…
The review demonstrated that neonatal injections of various pharmacological agents consistently led to detectable, long-term alterations in adult animals. These changes manifested across diverse domains, including aud…
This research highlights the neuroprotective potential of Semax and PGP by demonstrating their ability to upregulate Vegfa, a crucial factor for brain repair and recovery after ischemic injury. Enhancing Vegfa express…
The enhanced proteolytic stability of simple glyprolines is a critical finding for peptide drug design, particularly for developing therapeutics that require prolonged activity or specific routes of administration. Pe…
This study provides crucial insights into the molecular mechanisms underlying Semax's neuroprotective effects by demonstrating its ability to modulate gene expression related to inflammation and vascular repair after …
This research provides compelling evidence for the therapeutic potential of Semax as a neuroprotective agent against metal-induced toxicity, a critical factor in the pathogenesis of several debilitating neurodegenerat…
This research significantly reinforces the nootropic properties of Semax, demonstrating its capacity to both enhance learning in specific contexts and facilitate the recovery of learned behaviors following disruption.…
This research suggests that semax could serve as a valuable adjunctive therapy for managing the lipid metabolism disturbances commonly seen in psoriasis patients with metabolic syndrome. Correcting these lipid abnorma…
This research provides compelling evidence for the potential of semax to act as a therapeutic intervention against neurodevelopmental issues caused by early-life exposure to SSRIs like fluvoxamine. Given the increasin…
This study provides compelling evidence for the hepatoprotective potential of Semax in mitigating stress-induced liver damage and dysfunction. The peptide's ability to normalize liver enzyme activities and protein syn…
These findings underscore Semax's profound potential to directly modulate and enhance synaptic function in neural pathways highly relevant to pain processing and overall neuronal excitability. By improving glutamaterg…
This research highlights that while Semax possesses general antioxidant properties, its effects on liver enzyme markers under stress are highly nuanced and dose- and context-dependent. The finding that higher doses ca…
This review significantly advances our theoretical understanding of Semax's mechanism of action, identifying transthyretin (Ttr) as a potential key mediator in its neuroprotective effects. Unraveling this specific pat…
This study provides compelling evidence for the neuroprotective properties of Semax against heavy metal-induced cognitive impairment. Given the widespread environmental exposure to heavy metals and their significant i…
This study provides critical insights into how subtle chemical modifications, like N-terminus acetylation, can profoundly impact the interaction of therapeutic peptides with essential metal ions. Understanding these s…
Sympathetic overactivity is a well-established driver of adverse cardiac events and poor prognosis following myocardial infarction. The findings that Semax peptide can moderate this activation, prevent sympathetic ner…
This study provides compelling evidence that Semax possesses significant neuroprotective and cognitive-enhancing properties in a preclinical model of ischemic stroke. The observed reduction in infarct volume and impro…
This chemoreactome analysis provides a comprehensive molecular blueprint for mexidol, clarifying its diverse pharmacological actions beyond its known antioxidant properties. The identification of its potential as an a…
Understanding the intricate interplay between the nervous and immune systems is critical for developing novel treatments for a wide array of chronic diseases. This review consolidates fragmented knowledge, providing a…
Semax's ability to reduce excessive and potentially detrimental sympathetic innervation growth after MI is a highly significant finding, as dysregulated nerve growth can contribute to dangerous arrhythmias and further…
This study provides compelling evidence that Semax can significantly enhance neurological recovery and reduce disability in ischemic stroke patients, regardless of the disease stage. The observed improvements in both …
This research provides experimental substantiation for Semax's role as an immunomodulator, highlighting its potential to counteract the detrimental effects of stress on the immune system. Given that chronic stress is …
This novel iPSC-based platform offers a powerful, human-relevant tool for accelerating neuroprotective drug discovery, potentially reducing the reliance on less predictive animal models and improving the translatabili…
This study highlights the potential of peptide drugs like deltalicin as novel therapeutic agents for managing diabetic dyslipidemia. The finding that deltalicin was more potent than existing treatments suggests it cou…
This research provides compelling evidence for a novel protective role of Semax against stress-induced alterations in gut microbiota, highlighting its potential as a therapeutic agent for maintaining gut health under …
This research highlights the complex and context-dependent role of ACTH4-7-PGP (Semax) in pain modulation, moving beyond a simplistic view of its effects. Understanding this dual action could pave the way for more tar…
This study highlights the potential of Semax as a neuroprotective agent against the detrimental effects of early-life antidepressant exposure, which can lead to long-term behavioral and neurochemical deficits. Given t…
This research highlights PGC-1α activation as a promising therapeutic strategy for mitigating brain damage following ischemic stroke. By enhancing mitochondrial function and reducing oxidative stress, PGC-1α activator…
This research provides strong molecular evidence for Semax's neuroprotective properties, specifically its ability to mitigate the detrimental inflammatory response after ischemic stroke. By suppressing the mRNA expres…
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