18 studies on IGF-1-LR3 curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
This study provides crucial insights into the cellular mechanisms underlying the FecB mutation's prolificacy effect, demonstrating that ovarian cells from carriers are inherently more responsive to key fertility signa…
This research provides novel and critical mechanistic insights into how IGFBP-3 modulates cellular responses to growth factors, unequivocally identifying sphingosine kinase as a pivotal downstream effector in this pro…
This research highlights ALK4/5 inhibition as a highly promising therapeutic strategy for cancer cachexia, a condition with limited treatment options. By targeting a key pathway involved in muscle degradation, this ap…
This research provides compelling evidence that recombinant IGF-1 can induce targeted organ growth, rather than generalized, uncontrolled proliferation, in a developing fetus. This specificity is critical, as it sugge…
This research provides compelling evidence that GH and IGF-I can effectively counteract the decline in milk production during prolonged lactation, suggesting new avenues for intervention. The distinct yet complementar…
This research provides a fundamental understanding of how estradiol promotes muscle stem cell proliferation, highlighting the Epidermal Growth Factor Receptor (EGFR) as a critical mediator. Understanding this pathway …
This research provides critical insights into the intricate mechanisms governing coordinated cardiac and vascular development, particularly during vulnerable fetal stages. Understanding how IGF-1 orchestrates this bal…
This research provides compelling evidence that sustained elevated IGF-1 during fetal development directly programs pancreatic beta-cell dysfunction, leading to reduced glucose-stimulated insulin secretion. This is a …
This research highlights the fundamental importance of N-linked glycosylation for optimal IGF-1 signaling, providing crucial insights into cell biology and receptor function. Given that CHO cells are the primary indus…
This research highlights a complex interplay between IGF-1 and fetal glucose metabolism, suggesting that the in vivo effects of IGF-1 LR3 on insulin secretion are not solely due to direct actions on pancreatic beta ce…
This research highlights a critical insight into Alzheimer's disease pathology, suggesting that interventions solely focused on modifying amyloid plaques may not always translate into tangible cognitive benefits. The …
This study suggests that IGF-1 LR3 may not be an effective therapeutic strategy for reversing late-gestation intrauterine growth restriction (IUGR), even when systemic levels of IGF-1 are significantly elevated. The f…
This research introduces a highly innovative, sustainable, and biologically active nerve conduit derived from a plant source, offering a compelling alternative to current nerve repair strategies. The successful integr…
This research highlights a highly promising therapeutic strategy for treating volumetric muscle loss, a condition with limited effective treatments. By demonstrating that localized and sustained delivery of IGF-1 via …
This study unequivocally highlights the severe public health risks associated with the use of unregulated black market growth-promoting products. Consumers are frequently exposed to mislabeled, contaminated, or entire…
The widespread and increasing misuse of peptides poses a significant threat to the integrity of sports and the long-term health of athletes. This comprehensive review provides crucial insights for anti-doping organiza…
Free, no account — handy when you're working with IGF-1-LR3.